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We intend to periodically reassess whether a payment model established under section 1899(i)(3) of the Act, including the payment of prepaid shared savings, continues to improve the quality and efficiency of items and services furnished to Medicare beneficiaries without resulting in additional program expenditures

It would also have a dramatic impact in countries like Singapore, Thailand, Chile, Peru and the USA, where over a third of cigarettes on the market are flavoured

In light of these insights, the continued pursuit of rigorous clinical and mechanistic studies will be critical to validate these observations and translate them into safe and effective targeted therapies accounting for the heterogeneity observed in IBD

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